nem
Nested Effects Models to reconstruct phenotypic hierarchies
The package 'nem' allows to reconstruct features of
pathways from the nested structure of perturbation effects. It
takes as input (1.) a set of pathway components, which were
perturbed, and (2.) high-dimensional phenotypic readout of
these perturbations (e.g. gene expression or morphological
profiles). The output is a directed graph representing the
phenotypic hierarchy.
| Author |
Holger Froehlich, Florian Markowetz, Achim Tresch, Christian
Bender, Matthias Maneck, Claudio Lottaz, Tim Beissbarth |
| Maintainer |
Christian Bender |
To install this package, start R and enter:
source("http://bioconductor.org/biocLite.R")
biocLite("nem")
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